Short notice is making it difficult to book advance appointments, as PM admits regional disparities

Inconsistent vaccine supply is making it difficult for GPs in England to book patient appointments more than a few days in advance, experts have warned, as the prime minister admitted there were significant disparities in local immunisation rates.

Doctors, NHS specialists and MPs told the Guardian that batches of the Pfizer and Oxford/AstraZeneca vaccine frequently arrived with only a couple of days’ notice, requiring last-minute planning and creating uncertainty for patients.

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